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铁皮石斛叶的化学成分研究
张春花1, 徐巧林2, 曾 雷2, 王 颂2, 罗青文2, 陈颖乐2
1.广东省林业科技推广总站;2.广东省森林培育与保护利用重点实验室 广东省林业科学研究院
摘要:
从铁皮石斛 (Dendrobium officinale) 叶的乙醇提取物中分离得到 12 个化合物。通过光谱数据分 析,分别鉴定为:4- 羟基苯乙酮 (1)、对羟基苯甲醛 (2)、丁香醛 (3)、α- 萘酚 (4)、香草酸 -4-O-β-D- 吡喃葡 萄糖苷 (5)、5- 羟甲基糠醛 (6)、 (3S,5R,6R,7E,9S)-3,5,6,9-tetrahydroxy-7-megastigmene (7)、(6R,9S)-9-hydroxymegastigma-4,7-dien-3-one-9-O-β-D- glucopyranoside (8)、 (3R,9R )-9-O-β-D-glucopyranosyl-3-hydroxy-7,8- didehydro-β-ionol (9)、cyclomargenol (10)、N-p- 香豆酰酪胺 (11)、肌苷 (inosine, 12)。化合物 4、5、7、8、 9、10 为首次从石斛属中分离获得,化合物 1、2、6、12 为首次自铁皮石斛植物中分离得到。
关键词:  铁皮石斛    化学成分  结构鉴定
DOI:
分类号:
基金项目:广东省林业科技创新专项(2020KJCX013);国家自然科学基金项目 (31500291)资助
Chemical Constituents from Leaves of Dendrobium officinale
ZHANG Chun-hua1, ZENG Lei2, Wang Song2, XU Qiao-lin2, CHEN Ying-le2, 12
1.Guangdong Provincial Forestry Technology Extension Station;2.Guangdong Provincial Key Laboratory of Silviculture,Protection and Utilization,Guangdong Academy of Forestry
Abstract:
Twelve compounds were isolated from the 95% ethanol extract of the leaves of Dendrobium officinale. On the basis of spectral data, their structures were identified as 4-hydroxy acetopenone (1), p-hydroxy benzaldehyde (2), syringaldehyde (3), α-naphthalenol (4), vanillic acid-4-O-β-D-glucopyranoside (5), 5-hydroxymethyl furfural (6), (3S,5R,6R,7E,9S)-3,5,6,9-tetrahydroxy-7-megastigmene (7), (6R,9S)-9-hydroxymegastigma-4,7-dien-3-one-9-O-β-D-glucopyranoside (8), (3R,9R)-9-O-β-D-glucopyranosyl-3-hydroxy-7,8- didehydro-β-ionol (9), cyclomargenol (10), N-p-coumaroyltyramine (11), inosine (12). Of these compounds, 1、 2、6、12 were isolated for the first time from this herb, and 4、5、7、8、9、10 were isolated for the first time from Dendrobium genus.
Key words:  Dendrobium officinale  leaves  chemical constituent  structural identification