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柚木的植物化学与药理学研究进展
王西洋, 黄桂华, 杨光, 梁坤南, 周再知
中国林业科学研究院热带林业研究所
摘要:
柚木Tectona grandis 树干通直,木材纹理优美,是世界著名的速生珍贵用材树种。树体含有 甲基蒽醌、拉帕醌和脱氧拉帕醌等活性成分,可抵抗白蚁和真菌侵害。柚木树皮、叶片、心材等部位富 含萘醌、蒽醌和类异戊二烯醌等次级代谢产物,以及三萜类、类固醇、木酚素、脂肪酯和酚类等植物化 学物质。药理上,柚木被证实具有抗氧化、消炎、解热、细胞毒性、镇痛、降血糖、伤口愈合等多重功 效。文章着重介绍柚木的植物化学和药理研究方面的最新进展,以及其后续开发利用潜力。
关键词:  柚木  植物化学  药理学  次级代谢产物
DOI:
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基金项目:国家自然科学基金(31800529)、“十三五”国家重点研发课题(2016YFD0600602)
Review on Phytochemical and Therapeutic Potential Research Progress of Tectona grandis
Wang Xiyang, Huang Guihua, Yang Guang, Liang Kunnan, Zhou Zaizhi
Research Institute of Tropical Forestry, CAF
Abstract:
Tectona grandis L. is one of the most valuable timber tree species in the world with straight trunks and beautiful wood texture. Due to the active ingredients such as tectoquinone, lapachol and deoxylapachol, it is resistant to termites and fungi. The bark, leaves, heartwood and other parts of T. grandis L. are rich in secondary metabolites such as naphthoquinone, anthraquinone and isoprenoid quinone, as well as phytochemicals such as triterpenes, steroids, lignans, fatty esters and phenols. Pharmacologically, teak has been proven to have multiple effects such as antioxidant, anti-inflammatory, antipyretic, cytotoxic, analgesic, hypoglycemic, and wound healing. This article focuses on the latest advances in phytochemical and pharmacological research of teak, and its potential for subsequent development and utilization.
Key words:  Teak  phytochemistry  pharmacology  secondary metabolites